Background: Proton pump inhibitors (PPIs) are widely used over counter drugs in Pakistan. Unjustified use of PPI is increasing .One concern of their use is spermatogenesis and male fertility.
Objective: To observe the detrimental effects of proton pump inhibitors on various parameters of semen of younger individuals of Hyderabad sindh Pakistan.
Duration of study: 1st June to 25thDec 2017.
Place of study: private Clinics of sadder Hyderabad sindh Pakistan.
Methodology: 109 patients were selected as per inclusion criteria. All were young subjects, age was 24 ±7.6 years. Mean duration of PPI was 2.5±2.7 months. None of subject was diagnosed infertility or sub fertility. Five parameters were assessed before and after PPI use. Sampling technique was non probability convenience. Statical software was SPSS 16. Student paired t test was used to calculate p value before and after PPI use. P value was considered <0.05 significant.
Results: There was no significant impact noted over five parameters of semen p value was only significant in semen volume <0.05.
Conclusion: There is no negative impact of PPI over five parameters of semen and male fertility.
Keywords:
Published on: Mar 14, 2019 Pages: 1-9
Full Text PDF
Full Text HTML
DOI: 10.17352/ijsrhc.000004
CrossMark
Publons
Harvard Library HOLLIS
Search IT
Semantic Scholar
Get Citation
Base Search
Scilit
OAI-PMH
ResearchGate
Academic Microsoft
GrowKudos
Universite de Paris
UW Libraries
SJSU King Library
SJSU King Library
NUS Library
McGill
DET KGL BIBLiOTEK
JCU Discovery
Universidad De Lima
WorldCat
VU on WorldCat
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."